Klaus Maier-Hein

Klaus Maier-Hein

Head of Medical Image Computing

German Cancer Research Center (DKFZ)

Publications

2026

The autoPET3 Challenge: Automated Lesion Segmentation in Whole-Body PET/CT – Multitracer Multicenter Generalization Jakob Dexl, Katharina Jeblick, Andreas Mittermeier, Balthasar Schachtner, Anna Theresa Stüber, Johanna Topalis, Maximilian R. Rokuss, Fabian Isensee, Klaus Maier-Hein, Hamza Kalisch, Jens Kleesiek, Constantin Seibold, Hussain Alasmawi, Lap Yan Lennon Chan, Yixuan Yuan, Alexander Jaus, Rainer Stiefelhagen, Pauline Ornela Megne Choudja, Konstantin Nikolaou, Christian la Fougère, Sergios Gatidis, Matthias P. Fabritius, Maurice Heimer, Gizem Abaci, Lalith Kumar Shiyam Sundar, Rudolf A. Werner, Jens Ricke, Clemens C. Cyran, Thomas Küstner, Michael Ingrisch arXiv Contrastive virtual staining enhances deep learning-based PDAC subtyping from H&E-stained tissue cores Maximilian Fischer, Alexander Muckenhuber, Robin Peretzke, Luay Farah, Constantin Ulrich, Sebastian Ziegler, Philipp Schader, Lorenz Feineis, Hanno Gao, Shuhan Xiao, Michael Götz, Marco Nolden, Katja Steiger, Jens T. Siveke, Lukas Endrös, Rickmer Braren, Jens Kleesiek, Peter Schüffler, Peter Neher, Klaus Maier-Hein The Journal of Pathology

2025

AutoPET Challenge on Fully Automated Lesion Segmentation in Oncologic PET/CT Imaging, Part 2: Domain Generalization Jakob Dexl, Sergios Gatidis, Marcel Früh, Katharina Jeblick, Andreas Mittermeier, Anna Theresa Stüber, Balthasar Schachtner, Johanna Topalis, Matthias P. Fabritius, Sijing Gu, Gowtham Krishnan Murugesan, Jeff VanOss, Jin Ye, Junjun He, Anissa Alloula, Bartłomiej W. Papież, Zacharia Mesbah, Romain Modzelewski, Matthias Hadlich, Zdravko Marinov, Rainer Stiefelhagen, Fabian Isensee, Klaus Maier-Hein, Adrian Galdran, Konstantin Nikolaou, Christian la Fougère, Moon-Sung Kim, Nico Kallenberg, Jens Kleesiek, Ken Herrmann, Rudolf A. Werner, Michael Ingrisch, Clemens C. Cyran, Thomas Küstner Journal of Nuclear Medicine Unlocking the potential of digital pathology: Novel baselines for compression Maximilian Fischer, Peter Neher, Peter Schüffler, Sebastian Ziegler, Shuhan Xiao, Robin Peretzke, David Clunie, Constantin Ulrich, Michael Baumgartner, Alexander Muckenhuber, Silvia Dias Almeida, Michael Götz, Jens Kleesiek, Marco Nolden, Rickmer Braren, Klaus Maier-Hein Journal of Pathology Informatics Learned Image Compression for HE-Stained Histopathological Images via Stain Deconvolution Maximilian Fischer, Peter Neher, Tassilo Wald, Silvia Dias Almeida, Shuhan Xiao, Peter Schüffler, Rickmer Braren, Michael Götz, Alexander Muckenhuber, Jens Kleesiek, Marco Nolden, Klaus Maier-Hein Medical Optical Imaging and Virtual Microscopy Image Analysis

2024

Real-world federated learning in radiology: hurdles to overcome and benefits to gain Markus Ralf Bujotzek, Ünal Akünal, Stefan Denner, Peter Neher, Maximilian Zenk, Eric Frodl, Astha Jaiswal, Moon-Sung Kim, Nicolai R Krekiehn, Manuel Nickel, Richard Ruppel, Marcus Both, Felix Döllinger, Marcel Klaus Opitz, Thorsten Persigehl, Jens Kleesiek, Tobias Penzkofer, Klaus Maier-Hein, Andreas Bucher, Rickmer Braren Journal of the American Medical Informatics Association Longitudinal Segmentation of MS Lesions via Temporal Difference Weighting Maximilian R. Rokuss, Yannick Kirchhoff, Saikat Roy, Balint Kovacs, Constantin Ulrich, Tassilo Wald, Maximilian Zenk, Stefan Denner, Fabian Isensee, Philipp Vollmuth, Jens Kleesiek, Klaus Maier-Hein arXiv Metrics reloaded: recommendations for image analysis validation Lena Maier-Hein, Annika Reinke, Patrick Godau, Minu D. Tizabi, Florian Buettner, Evangelia Christodoulou, Ben Glocker, Fabian Isensee, Jens Kleesiek, Michal Kozubek, Mauricio Reyes, Michael A. Riegler, Manuel Wiesenfarth, A. Emre Kavur, Carole H. Sudre, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, Tim Rädsch, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Arriel Benis, Matthew B. Blaschko, M. Jorge Cardoso, Veronika Cheplygina, Beth A. Cimini, Gary S. Collins, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Robert Haase, Daniel A. Hashimoto, Michael M. Hoffman, Merel Huisman, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Alan Karthikesalingam, Florian Kofler, Annette Kopp-Schneider, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Björn Menze, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, Jens Petersen, Nasir Rajpoot, Nicola Rieke, Julio Saez-Rodriguez, Clara I. Sánchez, Shravya Shetty, Maarten van Smeden, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben Van Calster, Gaël Varoquaux, Paul F. Jäger Nature Methods Understanding metric-related pitfalls in image analysis validation Annika Reinke, Minu D. Tizabi, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, A. Emre Kavur, Tim Rädsch, Carole H. Sudre, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Arriel Benis, Florian Buettner, M. Jorge Cardoso, Veronika Cheplygina, Jianxu Chen, Evangelia Christodoulou, Beth A. Cimini, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Ben Glocker, Patrick Godau, Daniel A. Hashimoto, Michael M. Hoffman, Merel Huisman, Fabian Isensee, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Jens Kleesiek, Florian Kofler, Thijs Kooi, Annette Kopp-Schneider, Michal Kozubek, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Erik Meijering, Björn Menze, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, Jens Petersen, Susanne M. Rafelski, Nasir Rajpoot, Mauricio Reyes, Michael A. Riegler, Nicola Rieke, Julio Saez-Rodriguez, Clara I. Sánchez, Shravya Shetty, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben Van Calster, Gaël Varoquaux, Ziv R. Yaniv, Paul F. Jäger, Lena Maier-Hein Nature Methods Enhanced Diagnostic Fidelity in Pathology Whole Slide Image Compression via Deep Learning Maximilian Fischer, Peter Neher, Peter Schüffler, Shuhan Xiao, Silvia Dias Almeida, Constantin Ulrich, Alexander Muckenhuber, Rickmer Braren, Michael Götz, Jens Kleesiek, Marco Nolden, Klaus Maier-Hein Machine Learning in Medical Imaging Skeleton Recall Loss for Connectivity Conserving and Resource Efficient Segmentation of Thin Tubular Structures Yannick Kirchhoff, Maximilian R. Rokuss, Saikat Roy, Balint Kovacs, Constantin Ulrich, Tassilo Wald, Maximilian Zenk, Philipp Vollmuth, Jens Kleesiek, Fabian Isensee, Klaus Maier-Hein Computer Vision – ECCV 2024

2023

Prediction of Bone Marrow Biopsy Results From MRI in Multiple Myeloma Patients Using Deep Learning and Radiomics Markus Wennmann, Wenlong Ming, Fabian Bauer, Jiri Chmelik, André Klein, Charlotte Uhlenbrock, Martin Grözinger, Kim-Celine Kahl, Tobias Nonnenmacher, Manuel Debic, Thomas Hielscher, Heidi Thierjung, Lukas Thomas Rotkopf, Nikolas Stanczyk, Sandra Sauer, Anna Jauch, Michael Götz, Felix T Kurz, Kai Schlamp, Marius Horger, Saif Afat, Britta Besemer, Martin Hoffmann, Johannes Hoffend, Doris Kraemer, Ullrich Graeven, Adrian Ringelstein, David Bonekamp, Jens Kleesiek, Ralf Floca, Jens Hillengass, Elias K Mai, Niels Weinhold, Tim F. Weber, Hartmut Goldschmidt, Heinz-Peter Schlemmer, Klaus Maier-Hein, Stefan Delorme, Peter Neher Investigative Radiology

2022

Detailed Annotations of Chest X-Rays via CT Projection for Report Understanding Constantin Seibold, Simon Reiß, Saquib Sarfraz, Matthias A. Fink, Victoria L. Mayer, Jan Sellner, Moon-Sung Kim, Klaus Maier-Hein, Jens Kleesiek, Rainer Stiefelhagen 33rd British Machine Vision Conference Deep Learning–based Assessment of Oncologic Outcomes from Natural Language Processing of Structured Radiology Reports Matthias A. Fink, Klaus Kades, Arved Bischoff, Martin Moll, Merle Schnell, Maike Küchler, Gregor Köhler, Jan Sellner, Claus Peter Heußel, Hans-Ulrich Kauczor, Heinz-Peter Schlemmer, Klaus Maier-Hein, Tim F. Weber, Jens Kleesiek Radiology: Artificial Intelligence Metrics reloaded: Pitfalls and recommendations for image analysis validation Lena Maier-Hein, Annika Reinke, Evangelia Christodoulou, Ben Glocker, Patrick Godau, Fabian Isensee, Jens Kleesiek, Michal Kozubek, Mauricio Reyes, Michael A. Riegler, Manuel Wiesenfarth, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, A. Emre Kavur, Tim Rädsch, Minu D. Tizabi, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Peter Bankhead, Arriel Benis, M. Jorge Cardoso, Veronika Cheplygina, Beth A. Cimini, Gary S. Collins, Keyvan Farahani, Bram van Ginneken, Daniel A. Hashimoto, Michael M. Hoffman, Merel Huisman, Pierre Jannin, Charles E. Kahn, Alexandros Karargyris, Alan Karthikesalingam, Hannes Goetz Kenngott, Annette Kopp-Schneider, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Björn Menze, David Moher, Karel G. M. Moons, Henning Müller, Felix Nickel, Brennan Nichyporuk, Jens Petersen, Nasir Rajpoot, Nicola Rieke, Julio Saez-Rodriguez, Clarisa Sánchez Gutiérrez, Shravya Shetty, Maarten van Smeden, Carole H. Sudre, Ronald M. Summers, Abdel A. Taha, Sotirios A. Tsaftaris, Ben Van Calster, Gaël Varoquaux, Paul F. Jäger Pseudoprospective Paraclinical Interaction of Radiology Residents With a Deep Learning System for Prostate Cancer Detection: Experience, Performance, and Identification of the Need for Intermittent Recalibration Kevin Sun Zhang, Patrick Schelb, Nils Netzer, Anoshirwan Andrej Tavakoli, Myriam Keymling, Eckhard Wehrse, Robert Hog, Lukas Thomas Rotkopf, Markus Wennmann, Philip Alexander Glemser, Heidi Thierjung, Nikolaus von Knebel Doeberitz, Jens Kleesiek, Magdalena Görtz, Viktoria Schütz, Thomas Hielscher, Albrecht Stenzinger, Markus Hohenfellner, Heinz-Peter Schlemmer, Klaus Maier-Hein, David Bonekamp Investigative Radiology Combining deep learning and radiomics for automated, objective, comprehensive bone marrow characterization from whole-body MRI: a multicentric feasibility study Markus Wennmann, André Klein, Fabian Bauer, Jiri Chmelik, Martin Grözinger, Charlotte Uhlenbrock, Jakob Lochner, Tobias Nonnenmacher, Lukas Thomas Rotkopf, Sandra Sauer, Thomas Hielscher, Michael Götz, Ralf Floca, Peter Neher, David Bonekamp, Jens Hillengass, Jens Kleesiek, Niels Weinhold, Tim F. Weber, Hartmut Goldschmidt, Stefan Delorme, Klaus Maier-Hein, Heinz-Peter Schlemmer Investigative radiology DICOM Whole Slide Imaging for Computational Pathology Research in Kaapana and the Joint Imaging Platform Maximilian Fischer, Philipp Schader, Rickmer Braren, Michael Götz, Alexander Muckenhuber, Wilko Weichert, Peter Schüffler, Jens Kleesiek, Jonas Scherer, Klaus Kades, Klaus Maier-Hein, Marco Nolden Bildverarbeitung für die Medizin 2022 Fine-tuning BERT Models for Summarizing German Radiology Findings Siting Liang, Klaus Kades, Matthias A. Fink, Peter M. Full, Tim F. Weber, Jens Kleesiek, Michael Strube, Klaus Maier-Hein The 4th NAACL Clinical Natural Language Processing Workshop In Vivo Repeatability and Multiscanner Reproducibility of MRI Radiomics Features in Patients With Monoclonal Plasma Cell Disorders Markus Wennmann, Fabian Bauer, André Klein, Jiri Chmelik, Martin Grözinger, Lukas Thomas Rotkopf, Peter Neher, Regula Gnirs, Felix T Kurz, Tobias Nonnenmacher, Sandra Sauer, Niels Weinhold, Hartmut Goldschmidt, Jens Kleesiek, David Bonekamp, Tim F. Weber, Stefan Delorme, Klaus Maier-Hein, Heinz-Peter Schlemmer, Michael Götz Investigative Radiology

2021

The Federated Tumor Segmentation (FeTS) Challenge Sarthak Pati, Ujjwal Baid, Maximilian Zenk, Brandon Edwards, Micah Sheller, G. Anthony Reina, Patrick Foley, Alexey Gruzdev, Jason Martin, Shadi Albarqouni, Yong Chen, Russell Taki Shinohara, Annika Reinke, David Zimmerer, John B. Freymann, Justin S. Kirby, Christos Davatzikos, Rivka R. Colen, Aikaterini Kotrotsou, Daniel Marcus, Mikhail Milchenko, Arash Nazer, Hassan Fathallah-Shaykh, Roland Wiest Andras Jakab, Marc-Andre Weber, Abhishek Mahajan, Lena Maier-Hein, Jens Kleesiek, Björn Menze, Klaus Maier-Hein, Spyridon Bakas arXiv:2105.05874 [cs, eess] Common Limitations of Image Processing Metrics: A Picture Story Annika Reinke, Matthias Eisenmann, Minu D. Tizabi, Carole H. Sudre, Tim Rädsch, Michela Antonelli, Tal Arbel, Spyridon Bakas, M. Jorge Cardoso, Veronika Cheplygina, Keyvan Farahani, Ben Glocker, Doreen Heckmann-Nötzel, Fabian Isensee, Pierre Jannin, Charles E. Kahn, Jens Kleesiek, Tahsin Kurc, Michal Kozubek, Bennett A. Landman, Geert Litjens, Klaus Maier-Hein, Björn Menze, Henning Müller, Jens Petersen, Mauricio Reyes, Nicola Rieke, Bram Stieltjes, Ronald M. Summers, Sotirios A. Tsaftaris, Bram van Ginneken, Annette Kopp-Schneider, Paul F. Jäger, Lena Maier-Hein arXiv:2104.05642 [cs, eess] Adapting Bidirectional Encoder Representations from Transformers (BERT) to Assess Clinical Semantic Textual Similarity: Algorithm Development and Validation Study Klaus Kades, Jan Sellner, Gregor Koehler, Peter M. Full, T. Y. Emmy Lai, Jens Kleesiek, Klaus Maier-Hein JMIR medical informatics

2020

Joint Imaging Platform for Federated Clinical Data Analytics Jonas Scherer, Marco Nolden, Jens Kleesiek, Jasmin Metzger, Klaus Kades, Verena Schneider, Michael Bach, Oliver Lukas Sedlaczek, Andreas Bucher, Thomas J. Vogl, Frank Grünwald, Jens-Peter Kühn, Ralf-Thorsten Hoffmann, Jörg Kotzerke, Oliver Bethge, Lars Schimmöller, Gerald Antoch, Hans-Wilhelm Müller, Andreas Daul, Konstantin Nikolaou, Christian la Fougère, Wolfgang G. Kunz, Michael Ingrisch, Balthasar Schachtner, Jens Ricke, Peter Bartenstein, Felix Nensa, Alexander Radbruch, Lale Umutlu, Michael Forsting, Robert Seifert, Ken Herrmann, Philipp Mayer, Hans-Ulrich Kauczor, Tobias Penzkofer, Bernd Hamm, Winfried Brenner, Roman Kloeckner, Christoph Düber, Mathias Schreckenberger, Rickmer Braren, Georgios Kaissis, Marcus R. Makowski, Matthias Eiber, Andrei Gafita, Rupert Trager, Wolfgang A. Weber, Jakob Neubauer, Marco Reisert, Michael Bock, Fabian Bamberg, Jürgen Hennig, Philipp Tobias Meyer, Juri Ruf, Uwe Haberkorn, Stefan O. Schoenberg, Tristan Kuder, Peter Neher, Ralf Floca, Heinz-Peter Schlemmer, Klaus Maier-Hein JCO Clinical Cancer Informatics