Publications
2026
Extracting Medical Information From Unstructured Clinical Text Using Large Language Models to Enhance Health Care Interoperability: Proof-of-Concept Study
Bahadir Eryilmaz, Kamyar Arzideh, Mikel Bahn, Hendrik Damm, Sina Warmer, Henning Schäfer, Ahmad Idrissi-Yaghir, Tabea M. G. Pakull, Lea Jessica Albrecht, Jens Kleesiek, Georg C. Lodde, Christoph M. Friedrich, Elisabeth Livingstone, Dirk Schadendorf, Katarzyna Borys, Felix Nensa, René Hosch
Journal of Medical Internet Research
Explainable AI Predicts Hematoxicity from Cancer Treatment Using Multimodal Real-World Data
Julius Keyl, Philipp Keyl, Tim Lenfers, René Hosch, Niklas Kiermeyer, Simon Schallenberg, Moon-Sung Kim, Sebastian Bauer, Nikolaos Bechrakis, Michael Forsting, Dagmar Fuehrer-Sakel, Sied Kebir, Viktor Grünwald, Boris Hadaschik, Johannes Haubold, Ken Herrmann, Stefan Kasper, Rainer Kimmig, Stephan Lang, Tienush Rassaf, Alexander Roesch, Dirk Schadendorf, Jens T. Siveke, Martin Stuschke, Ulrich Sure, Matthias Totzeck, Anja Welt, Marcel Wiesweg, Jan Egger, Sylvia Hartmann, Grégoire Montavon, Felix Nensa, Klaus-Robert Müller, Martin Schuler, Jens Kleesiek, Frederick Klauschen
medRxiv
Automated Tumor International Classification of Diseases Coding of Real-World Pathology Reports Using Self-Hosted Large Language Models
Kamyar Arzideh, René Hosch, Amin Turki, Bahadir Eryilmaz, Mikel Bahn, Henning Schäfer, Ahmad Idrissi-Yaghir, Sameh Khattab, Amin Dada, Hideo A. Baba, Dirk Schadendorf, Martin Schuler, Jens Kleesiek, Sylvia Hartmann, Felix Nensa, Julius Keyl
JCO Clinical Cancer Informatics
Deep Learning-derived Sarcopenia Marker Predicts Benefit from Anti-EGFR Therapy in Patients with RAS Wild-Type Metastatic Colorectal Cancer
Julius Keyl, René Hosch, Fabian Hörst, Philipp Keyl, Amin Dada, Johannes Haubold, Jannis Straus, Jan Egger, Arndt Stahler, Annika Kurreck, Alexej Ballhausen, Sebastian Stintzing, Stefan Fruehauf, Lothar Müller, Annabel H. S. Alig, Tanja Trarbach, Sylvia Hartmann, Felix Nensa, Jens Kleesiek, Stefan Kasper, Martin Schuler, Dominik P. Modest
Clinical Cancer Research 2025
Automated CT-based sarcopenia assessment for risk stratification of patients undergoing colorectal cancer resection
Johannes Vogelsang, Gernot Pucher, Fabian Hörst, René Hosch, Johannes Haubold, Philipp Keyl, Christopher Sauer, David Albers, Peter Markus, Jan P. Neuhaus, Andreas D. Rink, Jürgen Treckmann, Ulf Peter Neumann, Kai Nassenstein, Michael Forsting, Hideo A. Baba, Jan Egger, Stefan Kasper, Martin Schuler, Felix Nensa, Jens Kleesiek, Julius Keyl
Clinical Surgical Oncology
Leveraging Sarcopenia index by automated CT body composition analysis for pan cancer prognostic stratification
Katarzyna Borys, Johannes Haubold, Julius Keyl, Maria A. Bali, Riccardo De Angelis, Kévin Brou Boni, Nicolas Coquelet, Judith Kohnke, Giulia Baldini, Lennard Kroll, Sara Schramm, Andreas Stang, Eugen Malamutmann, Jens Kleesiek, Moon-Sung Kim, Stefan Kasper, Jens T. Siveke, Marcel Wiesweg, Anja Merkel-Jens, Benedikt Michael Schaarschmidt, Viktor Grünwald, Sebastian Bauer, Arzu Oezcelik, Servet Bölükbas, Ken Herrmann, Rainer Kimmig, Stephan Lang, Jürgen Treckmann, Martin Stuschke, Boris Hadaschik, Lale Umutlu, Michael Forsting, Dirk Schadendorf, Christoph M. Friedrich, Martin Schuler, René Hosch, Felix Nensa
npj Digital Medicine
An automated information extraction model for unstructured discharge letters using large language models and GPT-4
Robert M. Siepmann, Giulia Baldini, Cynthia S. Schmidt, Daniel Truhn, Gustav Anton Müller-Franzes, Amin Dada, Jens Kleesiek, Felix Nensa, René Hosch
Healthcare Analytics
Automated 3D-Body Composition Analysis as a Predictor of Survival in Patients With Idiopathic Pulmonary Fibrosis
Luca Salhöfer, Francesco Bonella, Mathias Meetschen, Lale Umutlu, Michael Forsting, Benedikt Michael Schaarschmidt, Marcel Klaus Opitz, Jens Kleesiek, René Hosch, Sven Koitka, Vicky Parmar, Felix Nensa, Johannes Haubold
Journal of Thoracic Imaging
Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence
Julius Keyl, Philipp Keyl, Grégoire Montavon, René Hosch, Alexander Brehmer, Liliana Mochmann, Philipp Jurmeister, Gabriel Dernbach, Moon-Sung Kim, Sven Koitka, Sebastian Bauer, Nikolaos Bechrakis, Michael Forsting, Dagmar Führer-Sakel, Martin Glas, Viktor Grünwald, Boris Hadaschik, Johannes Haubold, Ken Herrmann, Stefan Kasper, Rainer Kimmig, Stephan Lang, Tienush Rassaf, Alexander Roesch, Dirk Schadendorf, Jens T. Siveke, Martin Stuschke, Ulrich Sure, Matthias Totzeck, Anja Welt, Marcel Wiesweg, Hideo A. Baba, Felix Nensa, Jan Egger, Klaus-Robert Müller, Martin Schuler, Frederick Klauschen, Jens Kleesiek
Nature Cancer
Why does my medical AI look at pictures of birds? Exploring the efficacy of transfer learning across domain boundaries
Frederic Jonske, Moon-Sung Kim, Enrico Nasca, Janis Evers, Johannes Haubold, René Hosch, Felix Nensa, Michael Kamp, Constantin Seibold, Jan Egger, Jens Kleesiek
Computer Methods and Programs in Biomedicine 2024
AI-derived body composition parameters as prognostic factors in patients with HCC undergoing TACE in a multicenter study
Lukas Müller, Aline Mähringer-Kunz, Timo Alexander Auer, Uli Fehrenbach, Bernhard Gebauer, Johannes Haubold, Benedikt Michael Schaarschmidt, Moon-Sung Kim, René Hosch, Felix Nensa, Jens Kleesiek, Thierno D. Diallo, Michel Eisenblätter, Hanna Kuzior, Natascha Roehlen, Dominik Bettinger, Verena Steinle, Philipp Mayer, David Zopfs, Daniel Pinto dos Santos, Roman Kloeckner
JHEP Reports
Automated 3D-Body Composition Analysis as a Predictor of Survival in Patients With Idiopathic Pulmonary Fibrosis
Luca Salhöfer, Francesco Bonella, Mathias Meetschen, Lale Umutlu, Michael Forsting, Benedikt Michael Schaarschmidt, Marcel Klaus Opitz, Jens Kleesiek, René Hosch, Sven Koitka, Vicky Parmar, Felix Nensa, Johannes Haubold
Journal of Thoracic Imaging
Prognostic value of deep learning-derived body composition in advanced pancreatic cancer—a retrospective multicenter study
Julius Keyl, Andreas Bucher, F. Jungmann, René Hosch, A. Ziller, R. Armbruster, P. Malkomes, T. M. Reissig, Sven Koitka, I. Tzianopoulos, Philipp Keyl, K. Kostbade, David Albers, Peter Markus, Jürgen Treckmann, Kai Nassenstein, Johannes Haubold, Marcus R. Makowski, Michael Forsting, Hideo A. Baba, Stefan Kasper, Jens T. Siveke, Felix Nensa, Martin Schuler, Georgios Kaissis, Jens Kleesiek, Rickmer Braren
ESMO Open 2023
Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence
Julius Keyl, Philipp Keyl, Grégoire Montavon, René Hosch, Alexander Brehmer, Liliana Mochmann, Philipp Jurmeister, Gabriel Dernbach, Moon-Sung Kim, Sven Koitka, Sebastian Bauer, Nikolaos Bechrakis, Michael Forsting, Dagmar Fuehrer-Sakel, Martin Glas, Viktor Gruenwald, Boris Hadaschik, Johannes Haubold, Ken Herrmann, Stefan Kasper, Rainer Kimmig, Tienush Rassaf, Alexander Roesch, Dirk Schadendorf, Jens T. Siveke, Martin Stuschke, Ulrich Sure, Matthias Totzeck, Anja Welt, Marcel Wiesweg, Hideo A. Baba, Felix Nensa, Jan Egger, Klaus-Robert Mueller, Martin Schuler, Frederick Klauschen, Jens Kleesiek
medRxiv
Contrast Agent Dose Reduction in MRI Utilizing a Generative Adversarial Network in an Exploratory Animal Study
Johannes Haubold, Gregor Jost, Jens Matthias Theysohn, Johannes Maximilian Ludwig, Yan Li, Jens Kleesiek, Benedikt Michael Schaarschmidt, Michael Forsting, Felix Nensa, Hubertus Pietsch, René Hosch
Investigative Radiology 2022
Deep learning-based assessment of body composition and liver tumor burden for survival modeling in advanced colorectal cancer
Julius Keyl, René Hosch, Aaron Berger, Oliver Ester, Tobias Greiner, Simon Bogner, Jürgen Treckmann, Saskia Ting, Brigitte Schuchmacher, David Albers, Peter Markus, Marcel Wiesweg, Michael Forsting, Felix Nensa, Martin Schuler, Stefan Kasper, Jens Kleesiek
Journal of Cachexia, Sarcopenia and Muscle
Biomarkers extracted by fully automated body composition analysis from chest CT correlate with SARS-CoV-2 outcome severity
René Hosch, Simone Kattner, Marc Moritz Berger, Thorsten Brenner, Johannes Haubold, Jens Kleesiek, Sven Koitka, Lennard Kroll, Anisa Kureishi, Nils Flaschel, Felix Nensa
Scientific Reports
CT-derived body composition analysis could possibly replace DXA and BIA to monitor NET-patients
Lennard Kroll, Annie Mathew, Giulia Baldini, René Hosch, Sven Koitka, Jens Kleesiek, Christoph Rischpler, Johannes Haubold, Dagmar Führer, Felix Nensa, Harald Lahner
Scientific Reports
Artificial intelligence guided enhancement of digital PET: scans as fast as CT?
René Hosch, Manuel Weber, Miriam Sraieb, Nils Flaschel, Johannes Haubold, Moon-Sung Kim, Lale Umutlu, Jens Kleesiek, Ken Herrmann, Felix Nensa, Christoph Rischpler, Sven Koitka, Robert Seifert, David Kersting
European Journal of Nuclear Medicine and Molecular Imaging
Contrast Media Reduction in Computed Tomography With Deep Learning Using a Generative Adversarial Network in an Experimental Animal Study
Johannes Haubold, Gregor Jost, Jens Matthias Theysohn, Johannes Maximilian Ludwig, Yan Li, Jens Kleesiek, Benedikt Michael Schaarschmidt, Michael Forsting, Felix Nensa, Hubertus Pietsch, René Hosch
Investigative Radiology 
