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Conference paper 2026

Enforcing Anatomical Symmetry with Euclidean Distance Transforms for Low-Field MRI Bilateral Structure Segmentation

Zdravko Marinov, Jens Kleesiek, Rainer Stiefelhagen

Low Field Pediatric Brain Magnetic Resonance Image Segmentation and Quality Assurance

DOI
Enforcing Anatomical Symmetry with Euclidean Distance Transforms for Low-Field MRI Bilateral Structure Segmentation

Abstract

Accurate segmentation of subcortical brain structures in MRI is essential for the study of neurodevelopment, particularly in pediatric populations. While low-field MRI scanners offer a cost-effective and safer alternative to high-field systems—especially eliminating the need for sedation in young children—they present challenges due to lower image resolution and signal-to-noise ratio. In this work, we propose a symmetry-aware post-processing strategy to improve the segmentation of bilateral structures in low-field MRI. We first train baseline U-Net models for the segmentation of eight anatomical structures, including hippocampi, in the LISA 2025 pediatric low-field MRI dataset. While these models achieve reasonable accuracy, we observe frequent violations of anatomical symmetry in their predictions. To address this, we introduce a novel correction step that explicitly enforces plausible anatomical symmetry by identifying discrepancies between hemispheres and applying deformation fields anchored by the dominant structure from each symmetric pair. This post-hoc alignment improves segmentation quality for all symmetric targets, particularly the hippocampi. Our approach highlights the importance of leveraging anatomical priors in low-resource imaging scenarios and paves the way for more reliable analyses in global health contexts(Code: https://github.com/Zrrr1997/LISA_2025_cvhci).
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